Endocrine Abstracts

Introduction: Gynecomastia is a benign excessive proliferation of glandular tissue in the male breast and results from an increased breast estrogen/androgen activity ratio. It may be physiological (infancy, puberty or aging) or pathological. The most common cause is drug-induced. Although hyperthyroidism is a rare cause(1.5%), gynecomastia occurs in up to 25-40% of males with Graves’ disease and is often undiagnosed. Its development as the first manifestation of this thyr...

Introduction: Vitamin B1 (VB1) deficiency can occur in patients with obesity and after bariatric surgery (BS). Nevertheless, pre-operative measurements of VB1 are still controversial. The relationship between serum VB1 and weight loss after BS has not been reported previously.Objectives: To study the association between pre-operative VB1 levels and weight loss after BS.Methods: Retrospective study of patients submitted to bariatric...

Lentigo malign melanoma corresponds to the main histological type of melanomas ‘in situ’, particularly affecting Caucasian elderly exposed chronically to the ultraviolet rays. The therapeutic course should be surgical, with careful resection of the tumor, allowing free and wide margins. Follicular thyroid carcinoma corresponds to the second most common histological type characterized as a well differentiated neoplasm. It presents markedly vascular dissemination, bein...

Thyroid hypophyseal adenomas correspond to about 0.5 to 1% of pituitary adenomas. Tumor hypersecretion of TSH may also be present in plurihormonal adenomas that simultaneously secrete growth hormone and/or prolactin or FSH and LH glycoprotein hormones. A 37-year-old patient complaining of ears, hands, feet and face growth for 1 year. He reported amenorrhea for 04 years, sweating and joint pains. Associated comorbidities: Systemic arterial hypertension for 4 years in the use of...

Introduction: Hyperglycaemia has been associated with worse maternal and foetal outcomes as well as higher risk for future type 2 diabetes (T2D).Objectives: We study the association between glucose above diagnostic threshold (GADT) at gestational diabetes (GD) diagnosis and risk of perinatal complications and maternal glucose abnormalities at post-partum.Materials and Methods: Retrospective study based on the national register of G...

Introduction: Gestational diabetes (GD) is defined as a glucose intolerance firstly recognized during pregnancy and it is the severity of hyperglycaemia which is relevant to maternal and foetal risks. The American Diabetes Association (ADA) recommends screening before 15 weeks of gestation for women at risk, using standard diagnostic criteria, and defines early abnormal glucose metabolism as fasting glucose 110-125 mg/dl or HbA1c 5.9-6.4%. However, the benefit of treating wome...